Evaluation of a 4-day repeated-dose micronucleus test in rat glandular stomach and colon using aneugens and non-genotoxic non-carcinogens

HIGHLIGHTS

  • who: Emiko Okada from the (UNIVERSITY) have published the article: Evaluation of a 4-day repeated-dose micronucleus test in rat glandular stomach and colon using aneugens and non-genotoxic non-carcinogens, in the Journal: (JOURNAL)
  • what: The authors further evaluated the sensitivity and specificity of the MN test for the rat glandular stomach and colon using three aneugens (colchicine vinblastine sulfate and docetaxel hydrate) and two non-genotoxic non-carcinogens (sodium chloride and sucrose). In this study with aneugens, MN induction in hepatocytes was preliminarily evaluated. Before the analysis, a biological standard sample, malaria . . .

     

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