Local euchromatin enrichment in lamina-associated domains anticipates their re-positioning in the adipogenic lineage

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  • who: Julia Madsen-u00d8sterbye from the Department of Molecular of Medicine, University have published the Article: Local euchromatin enrichment in lamina-associated domains anticipates their re-positioning in the adipogenic lineage, in the Journal: (JOURNAL)
  • what: The authors demonstrate a repositioning of entire stand-alone LADs and of LAD edges as a prominent nuclear structural feature of early adipogenesis. The authors focus on the first 72 h of differentiation to examine the dynamics of early LAD repositioning during initiation of the adipogenic gene_expression program. The authors provide evidence of rearrangement of the genome in ASCs . . .

     

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