HIGHLIGHTS
- who: Yating Liu from the StJohn`s University, United States have published the Article: Inhibition of RNF182 mediated by Bap promotes non-small cell lung cancer progression, in the Journal: (JOURNAL)
- what: The authors provided evidence that RNF182 plays a critical role in suppressing NSCLC progression. The studies demonstrated that Bap induced RNF182 aberrant hypermethylation in A549 and PC9 cell lines, and the decreased expression of RNF182 is associated with aberrant hypermethylation. The study demonstrated that Bap exposure induces hypermethylation of RNF182 promoter in an AhR independent way as knockdown of AhR did not rescue . . .
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