Optogenetic low-frequency stimulation of principal neurons, but not parvalbumin-positive interneurons, prevents generation of ictal discharges in rodent entorhinal cortex in an in vitro 4-aminopyridine model

HIGHLIGHTS

• who: Elena Y. Proskurina and colleagues from the Almazov National Medical Research Centre, Akkuratova Street, StPetersburg, Russia have published the Article: Optogenetic Low-Frequency Stimulation of Principal Neurons, but Not Parvalbumin-Positive Interneurons, Prevents Generation of Ictal Discharges in Rodent Entorhinal Cortex in an In Vitro 4-Aminopyridine Model, in the Journal: (JOURNAL) of 17/Nov/2022
• what: Epileptiform Activity Next, the authors aimed to clarify the mechanism of the observed effect of LFLS with the help of a mathematical model. The model showed that o continued to be enhanced when the pumping current was . . .
  

   

  

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