Indolethylamine n-methyltransferase (inmt) is not essential for endogenous tryptamine-dependent methylation activity in rats

HIGHLIGHTS

  • who: Nicolas G. Glynos from the DepartmentUniversity of have published the article: Indolethylamine N-methyltransferase (INMT) is not essential for endogenous tryptamine-dependent methylation activity in rats, in the Journal: Scientific Reports Scientific Reports
  • what: The authors report for the first time the generation of a novel transgenic INMT-KO rat model, as well as comprehensive multi-species study of INMT in relation to tryptamine-dependent activity and the biosynthesis of NMT and DMT. Using a highly sensitive radiometric enzyme assay, the authors show that extracts from brain and lung tissues of both WT and . . .

     

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