HIGHLIGHTS
- who: Sara K. Young-Baird from the DepartmentUniversity, Bethesda, Maryland, USA have published the research: Pumping the brakes: A noncanonical RNA-binding domain in FMRP stalls elongating ribosomes, in the Journal: (JOURNAL)
- how: For this analysis FAM-labeled homopolymeric RNAs and truncated recombinant proteins containing the RGG and CTD were utilized in electrophoretic mobility shift assays and fluorescence polarization experiments.
SUMMARY
Published EDITORS` PICK HIGHLIGHT: FMRP: pumping the brakes on translation neuronal mRNAs primarily based on the local concentration of the protein and not mRNA sequence? Perhaps the function of FMRP . . .
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