HIGHLIGHTS
SUMMARY
There was no comprehensive genetic and transcriptional analysis of all key mitophagy genes in LUAD progression, prognosis and therapeutics. The authors performed a comprehensive analysis of the gene_expression, copy number variation and mutation of key mitophagy genes in the tumor progression of LUAD by using the data from The key mitophagy genes were selected by referring to a previous study which identified the mitophagy genes from Reactome database. The prognostic analysis was performed in the training group and validated by the TCGA-LUAD validation group, the whole TCGA-LUAD group and an external dataset . . .
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