HIGHLIGHTS
- who: Tomasz Gromowski from the (UNIVERSITY) have published the research work: Current view of liver cancer cell-of-origin and proposed mechanisms precluding its proper determination, in the Journal: (JOURNAL)
- what: The aim of this review is to summarize and evaluate the evidence supporting the role of hepatocytes, cholangiocytes and progenitor cells as CoO in liver cancer and to highlight possible mechanisms responsible for changing cell identity, a process that may confound prudent determination of CoO in liver cancer (summarized in Fig 1 and Table 1).
SUMMARY
Understood biology, which precludes . . .
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