HIGHLIGHTS
- who: Tifany T. Oommen et al. from the Tripler Army Medical Center, Department of Medicine, Jarrett White Road, Honolulu, HI, USA have published the Article: Case Report Pembrolizumab Induced Calcitriol-Mediated Hypercalcemia, in the Journal: Case Reports in Nephrology of 30/07/2022
SUMMARY
Te major mechanisms by which hypercalcemia of malignancy can occur are osteolytic metastasis, humoral hypercalcemia with secretion of parathyroid hormone-related protein, and tumor production of calcitriol. Hypercalcemia should suppress PTH levels and in response, decrease production of 1,25-dihydroxyvitamin D. Te lack of suppression of 1,25 . . .
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