Crispr medicine for blood disorders: progress and challenges in delivery

HIGHLIGHTS

• who: . et al. from the Miltenyi Biotec, Germany University of Freiburg Medical Center have published the paper: CRISPR medicine for blood disorders: Progress and challenges in delivery, in the Journal: (JOURNAL)

SUMMARY

After recognition of the protospacer-adjacent motif (PAM), Cas9, creates a double strand break (DSB) in the target site (Rodríguez-Rodríguez et_al, 2019; Zhao et_al, 2021). The CRISPR-Cas system has various important applications in medicine including identifying genes involved in different diseases, developing disease models, establishing diagnostic and therapeutic approaches, cancer immunotherapy and drug screening (Antony et_al, 2018b . . .

 



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