Enzyme-independent catabolism of cysteine with pyridoxal-5′-phosphate

HIGHLIGHTS

• who: Prajakatta Mulay from the Department have published the paper: Enzyme-independent catabolism of cysteine with pyridoxal-5u2032-phosphate, in the Journal: Scientific Reports Scientific Reports of 22/Dec/2022

SUMMARY

Different intermediates of PLP reaction with cysteine are hypothesized in the l­iterature13-17, which includes the formation of a Schiff base, hemimercaptal, and closed ring thiazolidine structure (Fig 2A). In the case of 1H-NMR spectroscopy, PLP and cysteine were reacted in deuterated water ­(D2O) at 37 °C in a 1:1 molar ratio for 2 h. PLP exhibits keto-enol . . .

 



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