Indole and azaindole halogenation catalyzed by the rebh enzyme variant 3-lsr utilizing co-puri e. coli reductase

HIGHLIGHTS

  • who: . and collaborators from the Aarhus University, Denmark have published the Article: Indole and azaindole halogenation catalyzed by the RebH enzyme variant 3-LSR utilizing co-puri E. coli reductase, in the Journal: (JOURNAL)
  • what: The authors report herein the halogenation of an extended panel of indole, azaindole and anthranilamide derivatives with RebH 3-LSR (3-LSR hereafter), a thermostable variant of RebH, with focus on production of brominated compounds, which are highly valuable precursors for transition metal-catalyzed cross-coupling reactions (Miyaura and Suzuki, 1995; Torborg and Beller, 2009; Poor et_al, 2014).
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