Recapitulating the pharmacological interactions of cetuximab with sunitinib and cisplatin in head and neck carcinoma cells in vitro

HIGHLIGHTS

  • who: Dib M. and colleagues from the of Ear, Nose and Throat Surgery, University Medicine Greifswald, Greifswald, Germany have published the research work: Recapitulating the Pharmacological Interactions of Cetuximab with Sunitinib and Cisplatin in Head and Neck Carcinoma Cells in vitro, in the Journal: (JOURNAL)
  • what: This study investigates the impact of cetuximab on the cytotoxicity of cisplatin and sunitinib using cells representative of head and neck carcinoma and the oral epithelium.
  • how: The following genes were analyzed EGFR (Hs01076090_m1) Pgp (Hs00184500_m1) BCRP Hs01053790_m1) OCT1 (Hs00427552_ m1) MATE1 (Hs00217320_m1) CTR1 (Hs00977266_g1) MRP4 (Hs00988721_m1 . . .

     

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