Genetic, dna methylation, and immune profile discrepancies between early-stage single primary lung cancer and synchronous multiple primary lung cancer

HIGHLIGHTS

  • who: Fenglei Yu from the (UNIVERSITY) have published the research: Genetic, DNA methylation, and immune profile discrepancies between early-stage single primary lung cancer and synchronous multiple primary lung cancer, in the Journal: (JOURNAL)
  • what: By comparing the genetic, epigenetic, and immune landscapes between sMPLC and SPLC, the study provides new insights into the biology and possible carcinogenesis of sMPLC, with implications for disease monitoring and future therapeutic interventions. The study demonstrated that sMPLC lesions had lower TMB levels than those from SPLC nodules (Fig 1A, Additional file 2: Table S2). The authors investigated gene . . .

     

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