Role of tunable gold nanostructures in cancer nanotheranostics: implications on synthesis, toxicity, clinical applications and their associated opportunities and challenges

HIGHLIGHTS

  • who: Akash Kumar and collaborators from the Nanomaterial Toxicology Laboratory, Systems Toxicology and Health Risk Assessment Group, CSIR-Indian have published the research: Role of Tunable Gold Nanostructures in Cancer Nanotheranostics: Implications on Synthesis, Toxicity, Clinical Applications and Their Associated Opportunities and Challenges, in the Journal: (JOURNAL)
  • what: The study showed that mSiO2 and PSS-coated gold nanorods showed significant toxicity, while PEG, dSiO2, and TiO2 caused no cellular damage. The study showed selective localization of the nanoconstruct in the tumor, and was retained for 48 h.

SUMMARY

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