A novel intergenic enhancer that regulates bdnf expression in developing cortical neurons

HIGHLIGHTS

• who: Emily Brookes from the for Molecular Cell Biology, University College London, Gower Street, London WC E BT, UK have published the research work: A novel intergenic enhancer that regulates Bdnf expression in developing cortical neurons, in the Journal: (JOURNAL) of January/20,/2023
• what: The authors show that the Bdnf gene is located in a previously undescribed sub-TAD, and that the gene is repositioned away from the nuclear periphery during neuronal differentiation.
• how: The enhancer-promoter loop that the authors identified with 4C-seq was also found in a recent study . . .
  

   

  

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