Ligand and structure-based approaches for the exploration of structure – activity relationships of fusidic acid derivatives as antibacterial agents

HIGHLIGHTS

  • who: . et al. from the Guangdong University of Technology, China have published the Article: Ligand and structure-based approaches for the exploration of structure - activity relationships of fusidic acid derivatives as antibacterial agents, in the Journal: (JOURNAL)
  • what: All in all, this study has provided a novel pharmacophore model to select antibacterial FA derivatives and studied the relationship between the structures and bioactivity. The model was then used to correlate the activities of these compounds with the Phase field data calculated from their 3D structures. In this study, the minimum standard value of Qfit was . . .

     

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