Phosphatidyl inositol 3-kinase (pi3k)-inhibitor cdz173 protects against lps-induced osteolysis

HIGHLIGHTS

  • who: Osteoclast et al. from the Jinan, China have published the research work: Phosphatidyl Inositol 3-Kinase (PI3K)-Inhibitor CDZ173 protects against LPS-induced osteolysis, in the Journal: (JOURNAL)
  • what: The authors demonstrate that the protective effect of CDZ173 against LPS-induced calvarial bone loss is by inhibiting osteoclast activation in_vivo.
  • how: The membrane was washed three times with TBST visualized with image quantla4000 imaging system (GE Healthcare Chicago Illinois United_States) and the results were analyzed using the ImageJ software. osteoclasts were isolated and then cultured for an additional 2 days in hydroxyapatite . . .

     

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