The chronification mechanism of orofacial inflammatory pain: facilitation by gper1 and microglia in the rostral ventral medulla

HIGHLIGHTS

  • who: ufeffWenwenufeff ufeffZhengufeff from the Chinese University of Hong Kong, China have published the paper: The chronification mechanism of orofacial inflammatory pain: Facilitation by GPER1 and microglia in the rostral ventral medulla, in the Journal: (JOURNAL)
  • what: The authors investigated the mechanism which GPER1 and microglia in the RVM influence and facilitate chronic orofacial pain. The authors found that PLC and PKC protein expression was significantly higher in the RVM of rats in the CFA group compared with that of rats in the CON group, while G15 injection significantly downregulated their expression in the RVM . . .

     

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