Novel ground-up 3d multicellular simulators for synthetic biology cad integrating stochastic gillespie simulations benchmarked with topologically variable sbml models

HIGHLIGHTS

SUMMARY

The integration of the NGSS (Next Generation Stochastic Simulator) into two unique multicellular simulation layers was pursued, with subsequent benchmarking of performances with and without this subcellular processing layer. The distinction between real-time and batch processed performances in multicellular simulation are not clear from the literature and is one of the critical design aspects to consider when developing a multicellular simulator (see Section 1.4). Linear brought forward to number maintain responsive UI rather and operating Linear scaling wasfor notbenchmarking achieved as the ofacells increased, there wassystem. a polscaling was not achieved as . . .

 



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