In vivo imaging of axonal transport in peripheral nerves of rodent forelimbs

HIGHLIGHTS

  • who: Neuronal Signaling ( et al. from the Centre University College BG, UK. have published the Article: In vivo imaging of axonal transport in peripheral nerves of rodent forelimbs, in the Journal: (JOURNAL) of 19/01/2023
  • what: Through injection of a fluorescently labelled, atoxic, binding fragment of the tetanus neurotoxin into the forepaw, which is taken up at nerve terminals and sorted into neurotrophin-containing signalling endosomes , the authors show that individual cargoes can be imaged and tracked in axons of the rodent forelimb. With this method, the authors aim to facilitate comparative transport analyses . . .

     

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