Grape seed proanthocyanidin extract targets p66shc to regulate mitochondrial biogenesis and dynamics in diabetic kidney disease

HIGHLIGHTS

• who: . and colleagues from the Chongqing Medical University, China have published the article: Grape seed proanthocyanidin extract targets p66Shc to regulate mitochondrial biogenesis and dynamics in diabetic kidney disease, in the Journal: (JOURNAL)
• what: The authors propose that GSPE may serve as a potential therapeutic medicine in protecting the kidney from hyperglycemic toxicity.
• how: The results showed that the relative expression of p66Shc in the NG + over-p66Shc group was significantly higher (p and amplt 0.05 Figure 7A) and that in HG + si-p66Shc group was lower than those in the HG . . .
  

   

  

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