Design and synthesis of (z)-2-(benzylamino)-5- benzylidenethiazol-4(5h)-one derivatives as tyrosinase inhibitors and their anti-melanogenic and antioxidant effects

HIGHLIGHTS

• who: Jieun Lee and collaborators from the Laboratory of Medicinal Chemistry, Department of Manufacturing Pharmacy, College of Pharmacy, Pusan National University, Busan, Republic of Korea have published the research work: Design and Synthesis of (Z)-2-(Benzylamino)-5- benzylidenethiazol-4(5H)-one Derivatives as Tyrosinase Inhibitors and Their Anti-Melanogenic and Antioxidant Effects, in the Journal: Molecules 2023, 848 of 21/Nov/2022
• what: In this study (BABT) were designed based on the structure of MHY2081 using a simplified approach.
• how: All experiments were carried out independently thrice. 10 u00b5L of SIN-1 . . .
  

   

  

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