Transient receptor potential ankyrin-1-expressing vagus nerve fibers mediate il-1β induced hypothermia and reflex anti-inflammatory responses

HIGHLIGHTS

• who: Harold A. Silverman from the Laboratory for Biomedical Sciences, Institute for Bioelectronic Medicine, Drive, Manhasset, NY, USA have published the Article: Transient Receptor Potential Ankyrin-1-expressing vagus nerve fibers mediate IL-1u03b2 induced hypothermia and reflex anti-inflammatory responses, in the Journal: (JOURNAL)
• what: We describe a previously unrecognized mechanism by which IL-1u03b2 activates afferent vagus nerve fibers to trigger hypothermia, a response which is abolished by selective silencing of neuronal TRPA1.
• future: Study is required to evaluate the potential relevance of these molecular pathways in vagus nerve IL-1u03b2 . . .
  

   

  

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