Bacterial sensing via neuronal nod2 regulates appetite and body temperature

HIGHLIGHTS

• who: Ilana Gabanyi et al. from the InstitutParis, FranceUniversity and have published the Article: Bacterial sensing via neuronal Nod2 regulates appetite and body temperature, in the Journal: (JOURNAL)
• what: The authors show that bacterial peptidoglycan plays a major role in mediating gut-brain communication via the Nod2 receptor. The authors show that Nod2 is expressed by a subset of hypothalamic neurons that respond to MDP from the intestine and regulate food consumption, body temperature, and associated behaviors. The authors show that MDP effects on food intake 5 are mediated via the GABAergic neurons in the . . .
  

   

  

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