S-series coelenterazine-driven combinatorial bioluminescence imaging systems for mammalian cells

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SUMMARY

    2023, 24, 1420. https://doi.org/10.3390/ijms24021420 2 of 17 To date, nCTZ has been targeted to improve the optical properties, such as intensity and color in BL imaging systems, through chemical modifications of the imidazopyrazinone backbone. The authors introduce a unique combinatorial bioluminescence imaging system, which simultaneously reports multiple BL indexes, i.e., BL intensity patterns and colors as the signatures with novel CTZ analogues named "S-series". For this study, the authors synthesized ten kinds of S-series CTZ analogues and characterized the BL intensities, spectra, BL intensity patterns, and . . .

     

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