3d osteogenic differentiation of human ipscs reveals the role of tgfβ signal in the transition from progenitors to osteoblasts and osteoblasts to osteocytes

HIGHLIGHTS

• who: Shunsuke Kawai from the DepartmentKyoto University have published the article: 3D osteogenic differentiation of human iPSCs reveals the role of TGFu03b2 signal in the transition from progenitors to osteoblasts and osteoblasts to osteocytes, in the Journal: Scientific Reports Scientific Reports
• what: The authors show using hiPSCs and mouse cell lines that the TGFu03b2 signal maintains the osteoblastic phenotype and its downregulation is critical for the differentiation to osteocytes. In the present study, the high proliferative capacity of hiPSCs was exploited to make a condensed cell aggregate within seven days, which led to the rapid . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.