Clinicopathological profile of medullary thyroid carcinoma—could we predict aggressive behavior?

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SUMMARY

    The circumscribed appearance, a characteristic of the tumor nodule in MTC in the initial stages of tumor development, was present in most cases in the pT1a and pT1b stages and only in a few cases in the pT2 stage. Of the 17 cases (28.8%) with sizes between 10 and 20 mm, two cases (11.76%) were associated with lymph node metastasis, and of the 21 cases (35.5%) with sizes between 20 and 40 mm, 10 cases (47.6%) had positive lymph nodes; these values are close to those cited in the literature . . .

     

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