Modeling bile duct ischemia and reoxygenation injury in human cholangiocyte organoids for screening of novel cholangio-protective agents

HIGHLIGHTS

  • who: Shaojun Shi from the Department of Surgery, Erasmus MC Transplant Institute, University Medical Center, Rotterdam CE, the Netherlands have published the Article: Modeling bile duct ischemia and reoxygenation injury inu00a0human cholangiocyte organoids for screening of novel cholangio-protective agents, in the Journal: (JOURNAL)
  • what: The authors reported the use of ICOs culture to model ischemic biliary Implications of all the available evidence The authors demonstrate that human ICOs cultures are feasible to model bile duct ischemia and reoxygenation injury in_vitro. The authors aimed to investigate the transcriptional profiles of ICOs stressed by H/R . . .

     

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