HIGHLIGHTS
- who: Victoria Moiseeva from the (UNIVERSITY) have published the research work: Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration, in the Journal: (JOURNAL) of 23/Dec/2021
- what: The authors demonstrate that senescent cells are integral regenerative niche components that repress regeneration at all stages of life. The authors provide evidence that, after injury, a subset of niche cells accumulates ROS and DNA damage beyond a threshold, which leads to senescence and regenerative failure. The study provided a better definition of senescence in_vivo: despite being a state of irreversible arrest, senescence . . .
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