Molecular determinants of fibrillation in a viral amyloidogenic domain from combined biochemical and biophysical studies

HIGHLIGHTS

  • who: Juliet F. Nilsson and colleagues from the Laboratoire Architecture et Fonction des Macromolu00e9cules Biologiques (AFMB), UMR, Aix Marseille University and Centre National la (CNRS), Luminy, Case, , Marseille, France have published the article: Molecular Determinants of Fibrillation in a Viral Amyloidogenic Domain from Combined Biochemical and Biophysical Studies, in the Journal: (JOURNAL) of 20/01/2021
  • what: The authors show that the C-terminal half of PNT3 has an inhibitory effect on fibril formation that may act as a molecular shield and could thus be a key domain in the regulation of PNT3 fibrillation. The . . .

     

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