HIGHLIGHTS
- who: Masanori Ono and colleagues from the Department of Obstetrics and Gynecology, Tokyo Medical University, Tokyo, Japan have published the paper: The Circadian Clock, Nutritional Signals and Reproduction:A Close Relationship, in the Journal: (JOURNAL) of 14/Dec/2022
- how: Studies were carried out involving the conditional knockout of Bmal1 in ovarian granulosa cells or theca cells .
SUMMARY
In all mammalian species, including humans, circadian timing is essential for successful female reproduction. Arnt-like protein-1 (Bmal1) knockout in arginine vasopressin (AVP) neurons, kisspeptin neurons, GnRH neurons, or the whole body . . .
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