Senp6-mediated desumoylation of vegfr2 enhances its cell membrane transport in angiogenesis

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  • who: Qi He et al. from the Department of Pathophysiology, Guangdong Provincial Key Laboratory of Cardiac Function and Microcirculation, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China have published the article: SENP6-Mediated deSUMOylation of VEGFR2 Enhances Its Cell Membrane Transport in Angiogenesis, in the Journal: (JOURNAL)
  • what: This study investigated this using human umbilical vein endothelial cells (HUVECs) in conjunction with immunoblotting and immunofluorescence. This study shows that regulates trafficking from the Golgi to the endothelial cell surface. The authors show that following stimulation of endothelial cells by AGEs, SENP6 de-SUMOylated . . .

     

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