Physiology of pns axons relies on glycolytic metabolism in myelinating schwann cells

HIGHLIGHTS

  • who: Marie Deck and collaborators from the , Universitu00e9 Montpellier, Montpellier, France, Aix-Marseille University, MMG have published the paper: Physiology of PNS axons relies on glycolytic metabolism in myelinating Schwann cells, in the Journal: PLOS ONE of July/12,/2022
  • what: The authors show here that PKM2 is also upregulated in myelinating Schwann cells (mSC) of mature mouse sciatic nerve versus postnatal immature nerve.
  • how: Taken together these data indicated that PKM2 deletion did not affect the maintenance of the myelin sheet but resulted in a motor distal neuropathy in mice. In a . . .

     

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