HIGHLIGHTS
- who: Sergi Ferru00e9 from the University of Padua, Italy have published the Article: Functional and pharmacological role of the dopamine D4 receptor and its polymorphic variants, in the Journal: (JOURNAL)
- what: We reviewed the evidence conveying a significant role of D4R in the dopaminergic and noradrenergic modulation of the frontal cortico-striatal pyramidal neuron, with implications for the moderation of constructs of impulsivity as personality traits.
SUMMARY
The main functional and pharmacological properties of the D4R and its different D4R polymorphic variants have been elucidated only recently with studies addressing the . . .
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