Mitochondrial fission process 1 controls inner membrane integrity and protects against heart failure

HIGHLIGHTS

• who: Erminia Donnarumma from the (UNIVERSITY) have published the paper: Mitochondrial Fission Process 1 controls inner membrane integrity and protects against heart failure, in the Journal: (JOURNAL) of 22/Dec/2021
• what: The authors show that Mitochondrial Fission Process 1 (MTFP1) is an inner mitochondrial membrane (IMM) protein that is dispensable for mitochondrial division yet essential for cardiac structure and function. In line with the notion that increased proton leak is maladaptive for the heart, the study shows that MTFP1 loss in cardiomyocytes reduces the mitochondrial membrane potential as a result of increased proton leak . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.