HIGHLIGHTS
SUMMARY
Mesenchymal stem_cells (MSC) have been described as adult multipotent stem_cells, showing many relevant properties, spanning from the ability to immunomodulate and migrate to specifc sites of injury to the transdiferentiation into multiple cell types. For instance, adipose_tissue and bone marrow-derived MSC have shown diferences with respect to stem_cell content and epigenetic states. Besides, MSC obtained from diverse sources such as heart, dermis, bone marrow, and adipose_tissue have been reported as genotypically diferent, expressing diferent levels of embryonic stem_cell markers such as OCT-4, NANOG, and SOX-2, and biological properties including angiogenesis and . . .
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