HIGHLIGHTS
- who: Posted Date September and collaborators from the The University of Arizona https://orcidorg/0000-0002-3712- X have published the research work: Structure-based design of glycosylated oxytocin analogues with improved selectivity and antinociceptive activity, in the Journal: (JOURNAL)
- what: The authors aimed to optimize its druggability and elicit antinociception in mouse models. Since OT binds to a wide range of receptors, including those involved in physiological regulatory mechanisms the authors have no interest in modulating (e_g V1a receptor binding has been linked to bradycardia and body temperature changes after peripheral OT administration)41 . . .
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