Single-cell rna-sequencing reveals radiochemotherapy-induced innate immune activation and mhc-ii upregulation in cervical cancer

HIGHLIGHTS

  • who: Chao Liu from the (UNIVERSITY) have published the research: Single-cell RNA-sequencing reveals radiochemotherapy-induced innate immune activation and MHC-II upregulation in cervical cancer, in the Journal: (JOURNAL) of 17/05/2022
  • what: The authors performed scRNA-seq on 10 paired biopsies of CC tumors collected pre- and post-RCT and three samples of adjacent normal cervical tissues to characterize the CC ecosystem and identify dynamic changes in the tumor and its microenvironment. The authors aimed to perform validated testing on 2 validation cohorts: validation cohort 1, comprising 15 pairs of pre . . .

     

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