Design, synthesis, docking study, and antiproliferative evaluation of novel schiff base-benzimidazole hybrids with vegfr-2 inhibitory activity

HIGHLIGHTS

  • who: Hany M. Abd El-Lateef and colleagues from the Department of Chemistry, College of Science, King Faisal University, Al-Ahsa, Saudi Arabia have published the research work: Design, Synthesis, Docking Study, and Antiproliferative Evaluation of Novel Schiff Base-Benzimidazole Hybrids with VEGFR-2 Inhibitory Activity, in the Journal: Molecules 2023, 481 of /2023/
  • what: __SECTION__ Conclusions.
  • how: Analysis of the single dose 60 cell panel assay results showed that benzimidazole molecules 3a 3b 3d 3f 3l and 3n were found to be inactive while other benzimidazole molecules were active against some tumor . . .

     

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