Computational strategies for protac drug discovery

HIGHLIGHTS

  • who: Acta and colleagues from the Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Taipa, Macao, China have published the Article: Computational strategies for PROTAC drug discovery, in the Journal: (JOURNAL)
  • what: In this review, the authors focus on the discovery and optimization of new PROTAC compounds via molecular docking and virtual screening techniques, particularly molecular docking. Molecular docking may be able to help optimize candidates that are effective against both wild-type and mutant variants of a target, as has been demonstrated in some of the . . .

     

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