HIGHLIGHTS
SUMMARY
Since the accidental discovery of penicillin in 1928 by Sir Alexander Flemming, many other antibiotics belonging to different classes (e_g, tetracyclines, sulfonamides, amphenicols, aminoglycosides, β-lactams, etc.) have been determined based on their chemical structure or action mechanisms. Some recent findings in RIF delivery systems are concisely presented together with the analytical procedures employed for in_vitro RIF release monitoring during their preparation. The Q-AR method was also reported to be applied for the quantification of RIF in the presence of another compound (e_g, piperine and CC-I ). There are several methods based on RIF . . .
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