Applications of the reversible boronic acids/boronate switch to nucleic acids

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SUMMARY

    In this context, more than 15 years ago the authors initiated a research project aimed at combining the specific properties of boronic acids with those of nucleic_acids, exploiting in particular the diol function of ribonucleosides which thus appeared as a formidable recognition element. His current research interests focus on molecular recognition, DNA-based asymmetric catalysis and nucleic_acid bioconjugates. He co-authored more than 250 publications on various aspects of nucleic_acid chemistry focusing notably on the design of chemically modified DNAs and RNAs and their conjugates for therapeutic and diagnostic applications. The identification and characterization . . .

     

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