HIGHLIGHTS
SUMMARY
The effectiveness of a vaccine to prevent disease depends on the potentiality/efficiency of the vaccine and is indicated by the development of a specific humoral immune_response. Seroconversion is useful to measure the induction of an immune_response in the host and indicates the persistence of antibodies and immunity in the absence of disease. As a result of unexpected snowfall (uncommon in the geographic area of the experimental farm) causing a drastic and sudden drop in temperature, the booster was administered after 45 days according to Nickerson et_al, to prevent a distorted immune_response caused by . . .
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