Accelerated dna vaccine regimen provides protection against crimean-congo hemorrhagic fever virus challenge in a macaque model

HIGHLIGHTS

  • who: David W. Hawman from the (UNIVERSITY) have published the article: Accelerated DNA vaccine regimen provides protection against Crimean-Congo hemorrhagic fever virus challenge in a macaque model, in the Journal: (JOURNAL) of 22/07/2022
  • what: The authors show that two immunizations of this vaccine platform with both the NP and GPC antigens confer significant protection against CCHFV in infected macaques.
  • how: The ELISpot data indicated that cellular immunity in response to pNP and/or pGPC vaccination was low. Serum chemistries were completed on a VetScan VS2 Chemistry Analyzer (Abaxis Union City . . .

     

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