A functional analysis of 180 cancer cell lines reveals conserved intrinsic metabolic programs

HIGHLIGHTS

  • who: Subject Categories Cancer and collaborators from the (UNIVERSITY) have published the research work: A functional analysis of 180 cancer cell lines reveals conserved intrinsic metabolic programs, in the Journal: (JOURNAL)
  • what: In spite of the genetic variety of the tested 180 cell lines, the authors show that they cluster into two metabolic types, which the authors validated using lipidomics, 13C tracing, and pathway sensitivity analysis. A similar concept was successfully applied to gene_expression data (Segura-Lepe et al, 2019), and the authors demonstrate that it holds for metabolic systems with exemplary data set (Hackett . . .

     

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