Development of an efficient and precise adenine base editor (abe) with expanded target range in allotetraploid cotton (gossypium hirsutum)

HIGHLIGHTS

• who: Guanying Wang from the National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan, Hubei, Peopleu2019s Republic of China have published the research: Development of an efficient and precise adenine base editor (ABE) with expanded target range in allotetraploid cotton (Gossypium hirsutum), in the Journal: (JOURNAL)
• what: Nine adenine base editing tools, based on dCas9, nCas9, and dCpf1, were used in cotton for the first time.
• how: To assess the biased sites of A-to-G transitions in the sgRNA editing window the editing rate of each A-to-G transition . . .
  

   

  

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