The receptor for advanced glycation endproducts (rage) and its ligands s100a8/a9 and high mobility group box protein 1 (hmgb1) are key regulators of myeloid-derived suppressor cells

HIGHLIGHTS

  • who: Suzanne Ostrand-Rosenberg and collaborators from the Department of Pathology, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA have published the research work: The Receptor for Advanced Glycation Endproducts (RAGE) and Its Ligands S100A8/A9 and High Mobility Group Box Protein 1 (HMGB1) Are Key Regulators of Myeloid-Derived Suppressor Cells, in the Journal: Cancers 2023, 15, 1026. of /2023/
  • what: The impact of RAGE and its principal ligands S100A8/A9 and HMGB1 on multiple aspects of tumor progression has been established in numerous and diverse mouse and human cancers.
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