Allolobophora caliginosa coelomic fluid and extract alleviate glucocorticoid-induced osteoporosis in mice by suppressing oxidative stress and regulating osteoblastic/osteoclastic-related markers

HIGHLIGHTS

  • who: Marwa Ahmed Abdelfattah from the Faculty Cairo University have published the research: Allolobophora caliginosa coelomic fluid and extract alleviate glucocorticoid-induced osteoporosis in mice by suppressing oxidative stress and regulating osteoblastic/osteoclastic-related markers, in the Journal: Scientific Reports Scientific Reports
  • what: This study revealed a significant decrease in BMD, BMC, calcium, and phosphorus in the GIOP group compared to the control group, leading to hypomineralization of the bone matrix. This study has revealed a new mechanism regarding the action of AcE and AcCF on GIOP (Fig 6).
  • future: Research is needed . . .

     

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