HIGHLIGHTS
- who: Qi Xianghui and colleagues from the Jiangsu, China have published the research: Enhancing and stabilizing monoclonal antibody production by Chinese hamster ovary (CHO) cells with optimized perfusion culture strategies, in the Journal: (JOURNAL)
- what: Based on the above analysis, the objective of this study was to optimize the production process under perfusion culture strategy of the CHO cell line producing one anti-PD-1 mAb. This study provides some guidance for the mAb production by CHO cells with process engineering methods.
- how: The results indicated that continuous perfusion could maintain higher VCD . . .
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